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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
20.61
Human Site:
S1074
Identified Species:
32.38
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
S1074
S
Q
D
E
G
E
G
S
G
E
S
E
R
G
S
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
S1231
S
Q
D
E
G
E
G
S
G
E
S
E
R
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
S1085
S
Q
D
E
G
E
G
S
G
E
S
E
R
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
S1074
S
Q
D
E
G
E
G
S
G
E
S
E
R
G
S
Rat
Rattus norvegicus
P97690
1191
138430
S1041
K
Q
V
S
K
N
F
S
E
V
F
Q
K
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
S1095
S
Q
D
E
G
E
G
S
A
E
S
E
R
G
S
Chicken
Gallus gallus
Q90988
1189
134923
I1044
V
N
K
D
F
G
S
I
F
S
M
L
L
P
G
Frog
Xenopus laevis
O93309
1209
140704
Q1066
K
G
D
V
E
G
S
Q
S
Q
D
E
G
E
G
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
G1074
S
Q
D
E
G
E
G
G
D
S
E
R
A
S
S
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
G1074
S
Q
D
E
G
E
S
G
V
D
S
E
R
G
S
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
K1057
G
A
G
F
L
I
L
K
T
K
D
N
E
G
D
Honey Bee
Apis mellifera
XP_393700
1202
139436
T1059
H
A
Q
L
V
M
K
T
A
D
G
D
K
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
E657
E
L
Q
S
G
I
V
E
L
R
T
R
L
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
V1027
K
K
K
E
T
L
K
V
T
W
V
K
V
N
Q
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
D1086
H
D
E
S
I
D
V
D
M
D
A
E
S
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
93.3
0
13.3
53.3
73.3
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
93.3
6.6
20
53.3
80
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
0
0
0
14
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
54
7
0
7
0
7
7
20
14
7
0
0
14
% D
% Glu:
7
0
7
54
7
47
0
7
7
34
7
54
7
7
7
% E
% Phe:
0
0
0
7
7
0
7
0
7
0
7
0
0
0
0
% F
% Gly:
7
7
7
0
54
14
40
14
27
0
7
0
7
54
14
% G
% His:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
14
0
7
0
0
0
0
0
0
0
% I
% Lys:
20
7
14
0
7
0
14
7
0
7
0
7
14
0
0
% K
% Leu:
0
7
0
7
7
7
7
0
7
0
0
7
14
7
0
% L
% Met:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
0
7
0
0
0
0
0
7
0
14
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
54
14
0
0
0
0
7
0
7
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
14
40
0
0
% R
% Ser:
47
0
0
20
0
0
20
40
7
14
40
0
7
14
47
% S
% Thr:
0
0
0
0
7
0
0
7
14
0
7
0
0
0
0
% T
% Val:
7
0
7
7
7
0
14
7
7
7
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _